Around 250,000 yr ago , two oafish nestling were discover to excessive levels of wind in what is now France , according to novel enquiry . It ’s the oldest known showcase of lead photo in hominin remains — a discovery that ’s presenting an obvious interrogative : How could this have possibly happen so long ago ?

Anew paperpublished today in Science Advances exuviate new light on the environmental shape endured by Neanderthal children some 250,000 years ago . Ice Age winter , as the new research suggests , had a fundamental influence on the health of young Neanderthals . That ’s scarcely a surprisal — but the discovery of lead exposure among two Neandertal babe most certainly is .

Griffith University archeologist Tanya Smith , the lead author of the new field , made the discovery while impart a chemical analysis of Neanderthal teeth uncovered at an archaeologic site in southeast France . Teeth are like tree rings , chronicling an someone ’s history of chemical and environmental exposure . By studying the growth layer within ancient teeth , researchers can construct a history of photograph during the first three years of life .

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For the study , Smith and her colleagues analyse the teeth of two swinish youngster , known as specimens Payre 6 and Payre 336 , who lived 250,000 years ago . These two teeth , both molars , were recover sans skull , take a leak it difficult to value the overall health and consideration of the individuals . The tooth of an anatomically mod human shaver , Payre 1 , was also study . This tooth was found at the same site and dated to about 5,000 years ago .

“ It was n’t possible to delegate precise years to the three isolated tooth , but I ’ve forecast that the oafish first molar ( Payre 6 ) , which was only lightly worn , would have come from an adolescent , as adult Neanderthals show more worn teeth , ” Smith separate Gizmodo . “ The Neanderthal second grinder ( Payre 336 ) , was more haggard , and so I think this was more probable from a young adult . ”

As for the modern human ’s first grinder , it had not erupted or start to wear down , and the origin was uncomplete , so it was likely from a nestling who was around five long time previous , explain Smith .

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As Smith explain to Gizmodo , all three tooth analyze in the study were permanent .

“ First molars begin organize a few week before nascency and continue until about old age three , and 2nd molars from about three to six year of age , ” she said . “ They register the alchemy of what these individuals were eat and drinking as they mineralize [ within the layer of the teeth ] , which let in element in Milk River . ”

Indeed , by measuring levels of barium , oxygen , and take in the tooth , Smith ’s squad was able to track the kid ’s exposure to various climatic conditions , foods , and chemical substance at hebdomadary intervals . In turn , this information was related to the baby ’s health and pace of growth .

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“ This work reports a major breakthrough in the reconstruction of ancient climates , a significant factor in human evolution , as temperature and precipitation cycles influenced the landscapes and food resource our ancestors relied on , ” said Smith in a statement .

The Payre 6 child exhibited elevated levels of the ghost constituent atomic number 56 until nine month of age — an observation consistent with breastfeeding . These levels dropped somewhat and then remained temperate until the child reached the old age of 2.5 years , at which prison term the Ba levels dropped dramatically . This intimate a ablactate age of 2.5 years , which , interestingly , is the median age of weaning among pre - industrial humans .

significantly , this is a very minor sample distribution size , so the results require to be take with a grain of salt . What ’s more , the Payre 336 Neanderthal child did not demo the same barium spikes .

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“ We guess that the second molar [ from Payre 336 ] formed between around three to six years of historic period — so it is possible that the child was no longer nursing at this eld , ” Smith enjoin Gizmodo . “ Alternatively , the tooth show some environmental modification — meaning that elements in the burial environment may have obscure the nursing signal . This is a common complication of elemental studies . ”

Further analysis of other Neanderthal teeth would help to clarify these finding . It ’s hard to generalise Neandertal nursing patterns beyond this one sample .

By studying the oxygen isotopes in the teeth , the investigator were able to observe multi - class patterns in regards to environmental pic . The Payre 6 Neanderthal child , for example , was born in the fountain and was ablactate in the tumble .

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“ Mammals , including humans , show seasonal nativity patterns that relate to environmental cycle , ” the author write in the discipline . “ Our results for Payre 6 are ordered with the broad mammalian pattern of deliver offspring during periods of increase food availability . ”

Again , a not bad reflection , but a sample of one is not much to go by .

Revealingly , both Neanderthal children experienced wellness problem — described by the researchers as “ developmental disruptions”—during the nerveless periods . The stress enforce by the Ice Age wintertime , the writer surmise , took a toll on these unseasoned Neanderthals , who show signs of illness ( in the form of poorly develop tooth enamel ) during these catamenia .

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unusually , both the Payre 6 and Payre 336 Neanderthals were exposed to direct on at least two occasions during their former spirit . This is considered the oldest documented photograph to lead in hominin clay . As the how these children were disclose to lead , the scientist can only ruminate .

“ These high and acute spark advance lines are indicative of short - terminus vulnerability from ingestion of polluted food or piss or inhalation from fires moderate leash , ” the author indite in the subject area . “ Lead can also occur from mother ’ milk , but the divergent patterns of barium and lead in Payre 6 and the sharp confidential information band in both individuals suggest that mother ’ milk was not the elemental beginning of vulnerability . ”

No level of photograph to lead is take safe , but the health impacts can be subtle and sometimes detain . accordingly , the researchers are n’t sure if the tether had any effect on the health of these Neanderthal individuals .

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“ The lead line where high — in one suit 10 times more than setting measuring — but they did not cause any evident disturbance in their teeth , ” said Smith . “ We ca n’t know if these exposures had any consequence on their brain growth or noesis . It would be great to look at more prehistorical someone from this region in France to see how common these exposures might have been . ”

This exposure , the analysis indicate , happened during the tank season . What ’s more , this part of France is known to be rich in mineral deposits . It ’s potential that the Neanderthals , while seek tax shelter from the cold-blooded , pretend into caves , resulting in the exposure .

“ Traditionally , people think lead exposure occurred in population only after industrial enterprise , but these results show it happened prehistorically , before spark advance had been wide released into the environment , ” Christine Austin , a co - author of the study and an assistant professor at the Icahn School of Medicine at Mount Sinai , said in a statement .

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The Modern study is fascinating , but it suffers from the same matter that afflict so many other archaeological studies : deficient evidence from which to draw robust conclusions . These new insight into Neanderthals , while reveal and even plausible , need to be supported by further archeologic grounds . And indeed , that ’s just where this squad is lead next .

“ Our squad project to psychoanalyse more teeth … and investigate how tip exposure may have affected their wellness and how that may bear on to how our torso respond to conduct today , ” aver Austin .

In the interim , this study is yet another admonisher of the connection we share with our extinct full cousin . Like Neanderthals , we struggle with illnesses during the winter , and we nurse for around 2.5 twelvemonth . Yet for reasons that still are n’t completely unmortgaged , the recollective sovereignty of the Neanderthals hail to end around 45,000 class ago at the close of the last Ice Age . There ’s understandably   much still to learn about these remarkable human relatives .

Argentina’s President Javier Milei (left) and Robert F. Kennedy Jr., holding a chainsaw in a photo posted to Kennedy’s X account on May 27. 2025.

[ Science Advances ]

Human evolutionneanderthalsScience

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