A new drug that kills pain like marijuana, without getting you stoned

One cause why medical professional have buttonhole tirelessly to legalize aesculapian marijuana is that the drug can be a muscular painkiller . Now researchers have invented a drug that act just like marijuana , but never goes to your head .

And I intend that literally . The drug , glamorously named URB937 acts on your nervous system ’s cannabinoid sense organ – the same unity that make you stone if smoke pot – but does n’t regard those sensory receptor in your brain . According to a release from Nature , where the enquiry on URB937 was published last night :

The cannabinoid type 1 ( CB1 ) sensory receptor - which is known to mediate the effect of marihuana - also make out the body ’s own endocannabinoids . CB1 receptors are found both within the central nervous system ( CNS ) and the peripheral nervous system . . . Daniele Piomelli and colleagues have developed a speck that activates CB1 only outside the brain and spinal cord . The drug , with the computer code name URB937 , inhibits an enzyme that degrades one of the endocannabinoids , love as anandamide . In rotter , the scientists found that this drug raise anandamide levels , increase CB1 energizing and consequently alleviate several kinds of peripheral pain . URB937 entered the mental capacity , but unlike other CB1 activators , was quickly know and pump out of the brain . . .

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In other words , every part of your nervous system except the neurons in your mastermind is affect by this drug . It could be the silver bullet doc have been look for – all the aesculapian benefits of pot , without the getting waste part .

viaNature

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